兒科火星渦蟲(抗生素藥物篇)

Pediatric dose calculator

兒科火星渦蟲(抗生素藥物篇)

Made by 台大小兒內分泌科總醫師葉晉銘 (2026/02/09)

⚠️ 以下整理臨床常使用之抗生素，但非所有狀況皆適用，請參考 Uptodate/Micromedex。若有疑問請與 ID fellows 或臨床藥師討論。

⚠️ Newborn 的抗生素劑量請見 NICU 常用藥物部份。

📘 參考自台大小兒科住院醫師工作手冊

參數設定

歲 (Y)

月 (M)

體重 (kg)

身高 (cm)

BSA: -- m²

Penicillin G(3 MU/vial)	≤18歲: -- MU Q6H 0.15-0.4 MU/kg/d >18歲: 3-6 MU Q6H (12-24 MU/d) *Congenital syphilis (Max 24MU/d): ≤7天: -- MU Q12H 0.05 MU/kg/dose 8-28天: -- MU Q8H 0.05 MU/kg/dose >28天: -- MU Q6H 0.05 MU/kg/dose
OcillinaOxacillin (500 mg/vial)	-- mg Q6H 100-150 mg/kg/d Severe: -- mg Q6H 150-200 mg/kg/d Max 2 g/dose
ZiefmycinDicloxacillin (250 mg/cap)	<40 kg: -- mg Q6H 25-50 mg/kg/d Severe: -- mg Q6H 50-100 mg/kg/d ≥40 kg: 125-500 mg Q6H (MSSA: 500-1000 mg) Max 1 g/dose
AmpolinAmpicillin (500 mg/vial)	-- mg Q6H 100-200 mg/kg/d Severe: -- mg Q6H 200-400 mg/kg/d Max 12 g/day
Amolin/AmoxigranAmoxicillin (50 mg/ml)	-- mg Q12H 25-50 mg/kg/d High dose: -- mg Q12H 80-100 mg/kg/d IE Px: -- mg once 50 mg/kg Max 1g/dose (IE: 2g)
Amoxicillin(250 mg/cap)	-- cap Q12H 25-50 mg/kg/d High dose: -- cap Q12H 80-100 mg/kg/d
Unasyn/Amsulb(1000 mg + 500 mg/vial)	(Based on Ampicillin) -- mg Q6H 100-200 mg/kg/d Severe: -- mg Q6H 200-400 mg/kg/d
Curam(875 + 125 mg/tab) (80 + 11.43 mg/ml) (25 + 6.25 mg/ml)	(Based on Amoxicillin) <3月: -- mg Q12H 30 mg/kg/d ≥3月 & <40kg: -- mg Q8H 25-60 mg/kg/d ≥40kg: 1 tab Q12H or 500mg Q8H *High dose (Pneumonia/AOM): PO: -- mg BID 80-90 mg/kg/d Max 2g/dose
Tazocin(2000 + 250 mg/vial)	(Based on Piperacillin) <2月: -- mg Q6H 80 mg/kg/dose ≥2月: -- mg Q6H 300-400 mg/kg/d Max Pip 16 g/day

--- 1st Generation ---
CefaCefazolin (1 g/vial)	-- mg Q8H 50-100 mg/kg/d Severe: -- mg Q8H (or Q6H) 100-150 mg/kg/d *IE Px: -- mg once 50 mg/kg Max 2 g/dose (Adult 12g/d)
UlexinCephalexin (25 mg/mL)	-- mg Q6-8H 25-50 mg/kg/d Severe: -- mg Q6-8H 50-100 mg/kg/d Max 4 g/day
--- 2nd Generation ---
CetazoneCefmetazole (500 mg/vial)	-- mg Q8H 50-150 mg/kg/d Max 8 g/day; 黃疸新生兒避免
CexitinCefoxitin (1 g/vial)	-- mg Q8H 80 mg/kg/d Severe: -- mg Q6H 160 mg/kg/d Max 12 g/day
Furoxime/CeflourCefuroxime (750 mg/vial) Cefuroxime (250 mg/tab)	-- mg Q8H 75-100 mg/kg/d Severe: -- mg Q8H 100-200 mg/kg/d Max 1.5 g/dose
--- 3rd Generation ---
ClaforanCefotaxime (500 mg/vial)	-- mg Q8H 100-200 mg/kg/d Severe: -- mg Q6H 200-300 mg/kg/d Max 2 g/dose
CeftriaxoneSintrix (500 mg/vial)	-- mg QD 50-75 mg/kg/d Severe: -- mg Q12H 100 mg/kg/d Max 4 g/day
TatumcefCeftazidime (500 mg/vial)	-- mg Q8H 100-150 mg/kg/d Severe: -- mg Q8H 200-300 mg/kg/d Max 2 g/dose
FlumarinFlomoxef (1000 mg/vial)	-- mg Q8H 60-80 mg/kg/d Severe: -- mg Q8H 150 mg/kg/d Max 4 g/day
CeximeCefixime (100 mg/cap)	5-7.5 kg: 50 mg/day 7.6-10 kg: 75 mg/day 10.1-12.5 kg: 100 mg/day 12.6-20.5 kg: 150 mg/day 20.6-28 kg: 200 mg/day 28.1-33 kg: 250 mg/day 33.1-40 kg: 300 mg/day 40.1-45 kg: 350 mg/day >45 kg: 400 mg/day 頻次: Q12H-QD; Max 400mg
--- 4th & 5th Generation ---
MaxipimeCefepime (500 mg/vial)	-- mg Q12H 100 mg/kg/d Severe: -- mg Q8H 150 mg/kg/d Max 2 g/dose
ZinforoCeftaroline (600 mg/vial)	<2月: -- mg Q8H 6 mg/kg/dose 2月-2歲: -- mg Q8H 8 mg/kg/dose 2歲(≤33kg): -- mg Q8H 12 mg/kg/dose >33kg: 400mg Q8H or 600mg Q12H
BrosymCefop + Sulbactam (1000 mg+1000 mg/vial)	(Based on Cefoperazone) -- mg Q8H 20-40 mg/kg/d Serious: -- mg Q8H 80 mg/kg/d
ZaviceftaCeftaz + Avibactam (2000 mg + 500 mg)	(Based on Ceftazidime) <1月: -- mg Q8H 20 mg/kg/dose 1-2月: -- mg Q8H 30 mg/kg/dose 3-5月: -- mg Q8H 40 mg/kg/dose 6月-17歲: -- mg Q8H 50 mg/kg/dose ≥18歲: 2000 mg Q8H

Ciproxin IVCiprofloxacin (200 mg/vial)	-- mg Q12H 18-30 mg/kg/d Max 400 mg/dose
Ciproxin/Cinolone POCiprofloxacin (250 mg/tab)	-- mg Q12H 20-40 mg/kg/d Max 1.5 g/day
CravitLevofloxacin (250 mg/vial) Levofloxacin (500 mg/tab)	<5歲: -- mg Q12H 8-10 mg/kg/dose ≥5歲: -- mg QD 8-10 mg/kg/dose 健保限18歲以上

VancomycinIV (>1月) (500 mg/vial)	-- mg Q6H 10-15 mg/kg/dose 需依濃度/腎功能調整
VancoverVancomycin PO (125 mg/cap)	125 mg Q6H x 7-10 days (C. diff diarrhea) 口服不吸收
TargocidTeicoplanin (200 mg/vial)	<2月: LD -- mg 16 mg/kg MD -- mg QD 8 mg/kg 2月-12歲: LD -- mg Q12H (x3) 10 mg/kg MD -- mg QD 10 mg/kg >12歲: LD -- mg Q12H (x3) 12 mg/kg MD -- mg QD 12 mg/kg

InvanzErtapenem (1 g/vial)	3月-11歲: -- mg Q12H 15 mg/kg ≥12歲(≥50kg): 1 g QD
Imipenem/Cilastatin(500 + 500 mg/vial)	-- mg Q6H 60-100 mg/kg/d Max 4 g/day
MepemMeropenem (250 mg/vial)	-- mg Q8H 30-60 mg/kg/d Severe: -- mg Q8H 60-90 mg/kg/d Meningitis: -- mg Q8H 120 mg/kg/d Max 2 g/dose

ErythrocinErythromycin IV (500 mg/vial)	-- mg Q8H 10 mg/kg/d ⚠️ 注意事項：現少用於感染，常用增加腸胃蠕動。若用於PNA≤14天hypertrophic pyloric stenosis發生率提高十倍
ErythromycinErythromycin PO (250 mg/cap)	-- mg TID 25-50 mg/kg/d ⚠️ 注意事項：現少用於感染，常用增加腸胃蠕動。若用於PNA≤14天hypertrophic pyloric stenosis發生率提高十倍
Klaricid/ColirocinClarithromycin (500 mg/vial) (250 mg/tab) / (500 mg/tab)	-- mg Q12H 7.5 mg/kg/dose Max 1 g/day
ZithromaxAzithromycin (250 mg/tab) / (40 mg/mL)	Day 1: -- mg QD 10 mg/kg/d Day 2-5: -- mg QD 5 mg/kg/d Max 500 mg/day

--- Aminoglycosides ---
V-GentaGentamicin (80 mg/vial) (40 mg/mL)	-- mg QD 5-7 mg/kg/day Inhalation: 20-40mg Q12H
AcemycinAmikacin (500 mg/vial) (250 mg/mL)	-- mg QD 15 mg/kg/day Inhalation: 125-250mg Q12H
StreptomycinIM only (1 g/vial)	-- mg Q12H 20-40 mg/kg/day TB: -- mg QD 20-40 mg/kg/d
--- Others ---
ZyvoxLinezolid (600mg/bag) / (600 mg/tab)	<12歲: -- mg Q8H 20-30 mg/kg/d ≥12歲: 600 mg Q12H
CubicinDaptomycin (500 mg /vial)	-- mg QD -- mg/kg/dose
Doxymycin ECDoxycycline (100 mg/cap)	7-11 kg: 16.7 mg (1/6#) BID 11-16 kg: 25 mg (1/4#) BID 16-22 kg: 33.3 mg (1/3#) BID 22-32 kg: 50 mg (1/2#) BID 32-45 kg: 75 mg (3/4#) BID ≥45 kg: 100 mg (1#) BID
Menocik / MeroMinocycline (100 mg/vial) Minocycline (100 mg/cap)	(≥8歲, only if no choice) LD: -- mg 4 mg/kg MD: -- mg Q12H 2 mg/kg
ColimycinColistin (66.8 mg colistin/vial)	-- mg Q12H 2.5-5 mg/kg/day Inhalation: 33.4-66.8 mg Q12H
Clincin / LindacinClindamycin (300 mg/amp) Clindamycin (150 mg/cap)	-- mg Q8H 15-40 mg/kg/day Max 1.8 g/day
MetronidazoleMetronidazole (500 mg/btl) Metrozole (250 mg/tab)	IV: -- mg Q8H 30 mg/kg/d PO: -- mg TID 30 mg/kg/d
Baktar/Sevatrim/SulfacotrimTMP/SMX (T 80 mg/tab) (T 80 mg/amp) / (T 8 mg/mL)	(Based on TMP) Gen: -- mg Q12H 6-12 mg/kg/d PJP Tx: -- mg Q6H 15-20 mg/kg/d PJP Px: -- mg BID (TIW)

--- Polyenes ---
FungizoneAmphotericin B (50 mg/vial)	-- mg QD 0.5-1 mg/kg/d Max 1.5 mg/kg/day
AmBisomeLiposomal Ampho B (50 mg/vial)	Empiric: -- mg QD 3 mg/kg Systemic: -- mg QD 3-5 mg/kg
--- Azoles ---
DiflucanFluconazole (100 mg/vial) Fluconazole (50 mg/cap)	-- mg QD 6-12 mg/kg/d Max 800 mg/day
VfendVoriconazole (200 mg/vial) Voriconazole (200 mg/tab)	2-11歲 or <50kg: LD (IV/PO): -- mg Q12H 9 mg/kg MD (IV): -- mg Q12H 8 mg/kg MD (PO): -- mg BID 9 mg/kg ≥12歲 (≥50kg): LD (IV): -- mg Q12H 6 mg/kg MD (IV): -- mg Q12H 4 mg/kg MD (PO): 200-300 mg BID Adult <40kg: LD (IV): -- mg Q12H 6 mg/kg MD (IV): -- mg Q12H 4 mg/kg MD (PO): 100 mg BID
SporanoxItraconazole (100 mg/cap)	-- mg BID 5 mg/kg/dose Max 200 mg/day
PosanolPosaconazole (300 mg/vial)	2-17歲: LD: -- mg Q12H MD: -- mg QD 6 mg/kg ≥18歲: 300 mg QD (LD Q12H)
CresembaIsavuconazole (200 mg/vial) Isavuconazole (100 mg/cap)	<3歲: -- mg QD (LD Q8H) 8 mg/kg 3-17歲: -- mg QD (LD Q8H) 5.4 mg/kg Cap (6-17歲): -- mg QD (LD Q8H)
--- Echinocandins ---
CancidasCaspofungin (50 mg/vial)	-- mg QD 50-70 mg/m² Max 70 mg/day
MycamineMicafungin (50 mg/vial)	Tx: -- mg QD 2-4 mg/kg Px: -- mg QD 1 mg/kg
EraxisAnidulafungin (100 mg/vial)	MD: -- mg QD 1.5 mg/kg LD: 3 mg/kg (D1)

ZoviraxAcyclovir (250 mg/vial) (40 mg/ml)	HSV Encephalitis: -- mg Q8H 30-45 mg/kg/d (x 14-21 days) Neonatal HSV: -- mg Q8H 20 mg/kg/dose (x 14-21 days) Gingivostomatitis: IV: -- mg Q8H 15-30 mg/kg/d PO: -- mg QID 20 mg/kg VZV (Immuno-comp): IV: -- mg Q8H 30 mg/kg/d VZV (Normal): IV: 30 mg/kg/d PO: -- mg QID 80 mg/kg/d
ValtrexValacyclovir (500 mg/tab)	Chickenpox: -- mg TID 20 mg/kg/dose (x 5-10 days) HSV: -- mg BID 20 mg/kg/dose (x 5-7 days)
CymeveneGanciclovir (500 mg/vial)	Induction: -- mg Q12H 5 mg/kg (x 14-21 days) Maint: -- mg QD 5 mg/kg
ValcyteValganciclovir (450 mg/tab) (30 mg/mL)	CMV Px: -- mg QD 16-20 mg/kg/d
FoscarnetCMV Retinitis (6000 mg/250 ml/vial)	Induction: -- mg Q8H 180 mg/kg/d (x 14-21 days) Maint: -- mg QD 90-120 mg/kg/d
Tamiflu / ErafluOseltamivir (75 mg/cap) (15 mg/mL)	<12月: -- mg BID 3 mg/kg ≤15 kg: 30 mg BID 15-23 kg: 45 mg BID 23-40 kg: 60 mg BID >40 kg: 75 mg BID
XofluzaBaloxavir (20 mg/tab)	<20 kg: -- mg Once 2 mg/kg 20-80 kg: 40 mg Once ≥80 kg: 80 mg Once
RapiactaPeramivir (300 mg/60 mL)	-- mg QD -- mg/kg